sigmaplot 8 (Jandel Engineering)

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Jandel Engineering sigmaplot 8
Sigmaplot 8, supplied by Jandel Engineering, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sigmaplot+8/sigmaplot+software/pmc10058370-252-23-25
Average 90 stars, based on 1 article reviews

sigmaplot 8 - by Bioz Stars, 2026-09

90/100 stars

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Concentration Assay:

Article Title: Essential oil of Citrus lumia Risso: Phytochemical profile, antioxidant properties and activity on the central nervous system.
Article Snippet: Accepted Manuscript Essential oil of Citrus lumia Risso: Phytochemical profile, antioxidant properties and activity on the central nervous system.. Antonella Smeriglio, Susanna Alloisio, Francesco Maria Raimondo, Marcella Denaro, Jianbo Xiao, Laura Cornara, Domenico Trombetta PII: S0278-6915(17)30801-3 DOI: 10.1016/j.fct.2017.12.053 Reference: FCT 9498 To appear in: Food and Chemical Toxicology Received Date: 14 November 2017 Revised Date: 11 December 2017 Accepted Date: 22 December 2017 Please cite this article as: Smeriglio, A., Alloisio, S., Raimondo, F.M., Denaro, M., Xiao, J., Cornara, L., Trombetta, D., Essential oil of Citrus lumia Risso: Phytochemical profile, antioxidant properties and activity on the central nervous system., Food and Chemical Toxicology (2018), doi: 10.1016/ j.fct.2017.12.053.. This is a PDF file of an unedited manuscript that has been accepted for publication.

Article Title: Microelectrode array (MEA) platform as a sensitive tool to detect and evaluate Ostreopsis cf. ovata toxicity.
Article Snippet: In the last decade, the occurrence of harmful dinoflagellate blooms of the genus Ostreopsis has increased both in frequency and in geographic distribution with adverse impacts on public health and the economy.. Ostreopsis species are producers of palytoxin-like toxins (putative palytoxin and ovatoxins) which are among the most potent natural non-protein compounds known to date, exhibiting extreme toxicity in mammals, including humans.. Most existing toxicological data are derived from in vivo mouse assay and are related to acute effects of pure palytoxin, without considering that the toxicity mechanism of dinoflagellates can be dependent on the varying composition of complex biotoxins mixture and on the presence of cellular components.

Article Title: Multiparametric characterisation of neuronal network activity for in vitro agrochemical neurotoxicity assessment.
Article Snippet: The last few decades have seen the marketing of hundreds of new pesticide products with a forecasted expansion of the global agrochemical industry.. As several pesticides directly target nervous tissue as their mechanism of toxicity, alternative methods to routine in vivo animal testing, such as the Multi Electrode Array (MEAs)-based approach, have been proposed as an in vitro tool to perform sensitive, quick and low cost neuro-toxicological screening.. Here, we examined the effects of a training set of eleven active substances known to have neuronal or non-neuronal targets, contained in the most commonly used agrochemicals, on the spontaneous electrical activity of cortical neuronal networks grown on MEAs.

Article Title: The Essential Oil of Citrus lumia Risso and Poit. ‘Pyriformis’ Shows Promising Antioxidant, Anti-Inflammatory, and Neuromodulatory Effects
Article Snippet: .. To obtain the estimated IC 50 values, the normalized concentration–response curves of the single treatments were interpolated by a four-parameter logistic function using SigmaPlot 8 (Jandel Scientific): f(x) = Max + (Min − Max)/(1 + (ε/x) β ) (1) where the variable x is the concentration of the compound; the parameter Min is the minimum effect; the parameter Max is the maximum effect; the parameter ɛ is the concentration at the inflection point of the concentration–response curve, i.e., the concentration at which the effect is reduced by 50% (IC 50 ); and β is the parameter related to the maximum slope of the curve, which occurs at concentration ɛ. ..

Binding Assay:

Article Title: Polycystin-2 interacts with troponin I, an angiogenesis inhibitor.
Article Snippet: Polycystin-2 (PC2), encoded by the PKD2 gene, is mutated in 10-15% of autosomal dominant polycystic kidney disease (ADPKD) patients.. PC2 is a Ca2+-permeable nonselective cation channel and is present in kidney and many other organs.. Likewise, PKD2-mutated patients and mice exhibit extrarenal abnormalities.

Software:

Article Title: Troponin I binds polycystin-L and inhibits its calcium-induced channel activation.
Article Snippet: Polycystin-L (PCL) is an isoform of polycystin-2, the product of the second gene associated with autosomal dominant polycystic kidney disease, and functions as a Ca2+-regulated nonselective cation channel.. We recently demonstrated that polycystin-2 interacts with troponin I, an important regulatory component of the actin microfilament complex in striated muscle cells and an angiogenesis inhibitor.. In this study, using the two-microelectrode voltage-clamp technique and Xenopus oocyte expression system, we showed that the calcium-induced PCL channel activation is substantially inhibited by the skeletal and cardiac troponin I (60% and 31% reduction, respectively).

other:

Article Title: A modified mammalian tandem affinity purification procedure to prepare functional polycystin-2 channel.
Article Snippet: Analyzed data were fitted and plotted using Sigmaplot 8 (Jandel Scientific, San Rafael, CA) and expressed in the form of means S.E. (N ).

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